If you are vaccinated and catch covid, you do not clear the virus as quickly as the unvaccinated do.
Ahhhh, the brilliant Igor Chudov is back with another fascinating article. He is a great follow on Substack just FYI. In a new study by the New England Journal of Medicine, the researchers focused on the time it takes to eliminate the natural covid infection virus from persons vaccinated versus persons not vaccinated for covid. Here is the journal article. https://www.nejm.org/doi/full/10.1056/NEJMc2202092
What were the findings?
Approximately 31% of the participants who were vaccinated/boosted were still showing PCR viral loads consistent with ability to shed/spread the virus at day 10, whereas 6% of unvaccinated individuals were still showing viral loads consistent with ability to spread the virus at day 10.
“In other words: out of 100 boosted persons who catch Covid, 31 will be still carrying LIVE VIRUS on Day 10. Out of 100 unvaccinated persons, only 6 would test positive on Day 10 — over five TIMES fewer people.
As a word of warning, the study involved a relatively small amount of people, so statistical significance is probably not quite what we’d like it to be — but it shows what we saw all along in other news. This study needs to be replicated on a larger scale for validity and determine if the same results are replicated in future studies.
It also means that boosted people, who might feel better in a few days, would be contagious for a few MORE days after recovery, thus potentially becoming silent spreaders of Covid. So much for “stopping the spread”!
This ties into the Plaxovid failure in vaccinated people as well. We have discussed the anecdotal reports of people on Plaxovid who stated they got sick again around day 10-12 post positive covid test, and post Plaxovid treatment. Per the post by Igor: What Paxlovid is, is a biomolecular “snooze button” that suspends viral replication for 5 days. However, as we can see, one-third of the boosted people still carry live virus at 10 days due to delayed, or disabled, immune responses. Those persons would be likely to rebound on Paxlovid.
The numbers also match other calculations: my guesstimate of unvaccinated Paxlovid rebound was 12% — that is not too far from 6% of unvaccinated people in this study who carried live virus on Day 10. 31% of boosted people who still have live virus on Day 10, matches Twitter reports of 40-50% rebound rates in vaccinated people.
In other words, while we were fairly certain that Paxlovid does not work for vaccinated people, we were missing the most crucial proof: that the live virus is not clearing in the boosted. The study I mentioned above, provides early small sample size evidence for this.
It also exposes vaccines as merely “increasing tolerance” to Sars-Cov-2, as opposed to generating robust immune response that leads to rapid viral clearance.”
Too bad researchers are not studying with”gold standard” methodology. It will stay anecdotal likely confabulated with “ long covid” oncology must lead this crusade.
Hi Dr Jennifer, I have a couple of questions, 1) for this paper https://www.science.org/doi/epdf/10.1126/science.abq1841?utm_source=substack&utm_medium=email
They showed boosted gets BA1/2 antibodies post omicron infection, otherwise awful for other outcomes, so do you have any info on how long that antibody lasts, and/or how it works against BA4/5? Just haven’t seen any hybrid immunity studies against BA4/5 yet…would another booster mess up their BA1/2 antibodies?
2) a study Dr Been showed reinfection is worse each time (no difference between 0 and 2 doses for each severe outcomes), but other studies showing like 70-97% effectiveness against severe illnesses for both vax and natural immunity, so is reinfection suppose to be milder or worse now? =P
3) me and wife got flu shots in 2019 then a few months later she got alopecia and I had swollen hand with blisters (had them in ankles and knees apparently from scabies a year earlier), we recovered but I am worried about immune imprinting from that shot, can we still take supplements and good diet to have a rounded immune system or have we suppressed our old acquired antibodies? I realized I got quite sick with viruses or flu the yr after each of my flu shots that work recommended me to get a few yrs ago, I got about 3 between 2014-2019…
Thanks!