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Bird's avatar

Gain of function in Spike from Covid vs. Sars of the past = for example, furin cleavage site enabling Spike to enter cells.

Quote from Pfizer above: "... when a full virus does not contain any known gain of function mutations, such virus **may be engineered** to enable the assessment of antiviral activity in cells." As in, they use gain of function to get it into cells, which is what happened in Covid vs. Sars, and the mutation that sets apart the more mild Omicron vs. the worse Alpha / Delta.

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JWM_IN_VA's avatar

I'll honor the disclaimer and only say that there is some quite serious effort to firewall discussions of the OTA contracts and emergency powers laws.

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